A confluence of pre-existing structural factors and recent macroeconomic shocks are contributing to the aggravation of food insecurity in the Central African Republic. The government has a limited capacity to respond through social protection programs, due to fiscal and institutional fragility. Under the circumstances, the near-term response to reduce the adverse impacts includes increased humanitarian aid and resumption of donor support in the form of grants. In the medium to long term, policies to address the structural drivers of food insecurity should be part of government’s development agenda, acting on all four dimensions of food security—availability, access to, utilization and stability of food.